Search on: PHOSPHATIDYLINOSITOL DIACYLGLYCEROL-LYASE 
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Descriptor English:   Phosphatidylinositol Diacylglycerol-Lyase 
Descriptor Spanish:   Fosfatidilinositol Diacilglicerol-Liasa 
Descriptor Portuguese:   Fosfatidilinositol Diacilglicerol-Liase 
Synonyms English:   1-Phosphatidylinositol Phosphodiesterase  
Tree Number:   D08.811.277.352.640.700.700.500
D08.811.520.650.800
Definition English:   A phosphorus-oxygen lyase found primarily in BACTERIA. The enzyme catalyzes the cleavage of a phosphoester linkage in 1-phosphatidyl-1D-myo-inositol to form 1D-myo-inositol 1,2-cyclic phosphate and diacylglycerol. The enzyme was formerly classified as a phosphoric diester hydrolase (EC 3.1.4.10) and is often referred to as a TYPE C PHOSPHOLIPASES. However it is now known that a cyclic phosphate is the final product of this enzyme and that water does not enter into the reaction. 
Indexing Annotation English:   note X refs: TYPE C PHOSPHOLIPASES is also available
History Note English:   2004; use PHOSPHOTIDYLINOSITOL DIACYLGLYCEROL-LYASE (NM) 1980-2003 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   38148 
Unique Identifier:   D043265 

Occurrence in VHL:
 

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